A Canadian province has included a low-cost antidepressant on its list of treatments




The province of Ontario is the first in Canada, and probably currently the only one in the world, to recommend the economical and well-known antidepressant fluvoxamine for the treatment of patients with mild covid, who are at risk of aggravating diseases. requiring hospital treatment.


Source: Telegram.hr

Photo: Profimedia

Photo: Profimedia

Almost simultaneously, Don Hopkins University in Baltimore, USA, included fluvoxamine in its guidelines for treating patients with a mild clinical picture. It is recommended to take it within seven days of the onset of the first symptoms, provided the patient is not in the third trimester of pregnancy.

Croatian professor Robert Leakey cited fluvoxamine as a drug that has therapeutic potential in the treatment of covid. He also said that the former drug belongs to the group of antidepressants and works by inhibiting serotonin reactivation (SSRI).

Liki also said that a great deal of research from France has shown that the use of SSRIs has a protective effect on covids. The hypothesis of a beneficial effect of SSRI on coronavirus is based on its activation of the sigma1 receptor (S1R), which is responsible for regulating cytokine production in cells. Liki later said: “Fluvoxamine is a strong S1R agonist, and its binding to this receptor reduces cytokine synthesis and thus prevents the formation of cytokine tumors. In a double-blind clinical study published at the end of the year, According to JAMA’s top scientific journal, the Journal of the American Medical Association, in a group of 80 patients with covid who took fluvoxamine for 14 days immediately after diagnosis, no one had a worse clinical condition that required hospitalization or 72 patients developed clinical trials, which was the difference, which spoke in favor of the protective effect of fluvoxamine in SARS-CoV-2 infection.

Thus, Professor Liki warned of the possible efficacy of fluvoxamine, which is a selective serotonin reuptake inhibitor (SSRI), an antidepressant commonly used to treat depression and obsessive-compulsive disorder. Professor Liki also published a preliminary version of a study on the effectiveness of the drug fluvoxamine in the treatment of covid-infected patients in the portal of the British Journal of Clinical Pharmacology.

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